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Description: Human Keratinocyte growth factor-2 (KGF-2 or FGF-10) is a novel human protein that stimulates the repair of injured mucosal tissues. KGF-2 directly promotes wound-healing by stimulating the proliferation, migration and differentiation of epithelial cells, and has direct chemotactic effects on tissue remodeling. KGF-2 also appears to result in less scarring. Recombinant Human KGF-2 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 170 amino acids with molecular weight of about 19.3kD. Recombinant human KGF-2 is highly related to KGF-1(FGF-7) and binds to the same receptor as KGF-1 and shares 57% sequence homology. Recombinant KGF-2 is purified by proprietary chromatographic techniques. Source : Escherichia Coli. Physical Appearance : Sterile Filtered White lyophilized (freeze-dried) powder. Formulation : Lyophilized from a concentrated (1mg/ml) solution in water containing 40mM Sodium Phosphate buffer, pH 7.4 , 20 mM NaCl. Solubility : It is recommended to reconstitute the lyophilized KGF -2 in sterile 18M-cmH2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions. Stability : Lyophilized KGF-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18 . Upon reconstitution KGF-2 should be stored at 4 between 2-7 days and for future use below -18 . For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles. Amino-Acid Sequence :The sequence of the first five N-terminal amino acids was determined and was found to be Met-Ala-Leu-Gly-Asp. Dimers and aggregates :Less than 1% as determined by silver-stained SDS-PAGE gel analysis. Biological Activity :Recombinant human KGF-2 is fully biologically active when compared to standards. The specific activity is about 1.0 x 10 6 Units/mg.
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Recombinant human keratinocyte growth factor-2 (KGF-2/FGF-10) is a non-glycosylated polypeptide of 170 amino acids with a molecular weight of about 19.3kD, produced in E. coli. It stimulates the repair of injured mucosal tissues by promoting proliferation, migration, and differentiation of epithelial cells, and has chemotactic effects on tissue remodeling with reportedly less scarring. The protein shares 57% sequence homology with KGF-1 (FGF-7) and binds the same receptor. It is purified by proprietary chromatographic techniques and supplied as a sterile filtered white lyophilized powder, lyophilized from a 1 mg/ml solution in water containing 40 mM sodium phosphate buffer pH 7.4 and 20 mM NaCl. Reconstitution is recommended in sterile water at not less than 100 µg/ml. Lyophilized KGF-2 is stable at room temperature for three weeks but should be stored desiccated below -18 °C; after reconstitution it can be kept at 4 °C for 2–7 days or below -18 °C for longer storage with a carrier protein (0.1% HSA or BSA). Freeze-thaw cycles should be avoided. The N-terminal sequence begins Met-Ala-Leu-Gly-Asp, and dimers/aggregates are less than 1% by silver-stained SDS-PAGE. The product is described as fully biologically active compared to standard.
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Hangzhou Lion Biotechnology Co., Ltd. is a B2B supplier based in China, listed on Global Trade Plaza since October 2026. Use Inquire now or Chat with supplier to ask Hangzhou Lion Biotechnology Co., Ltd. for prices, specifications and documents for Recombinant human keratinocyte growth factor-2.
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