Lysostaphin, an endopeptidase specific for the cell wall peptidoglycan of staphylococcus, is an extremely potent antistaphylococcal agent. Its molecular weight is 27kDa and is comprised of 246 amino acids. The isoeletric point of it is 10.5-11.0. The key enzymatic reaction of lysostaphin is the specific cleavage of the Gly-Gly bond in the pentaglycine subunit of the cell wall peptidoglycan and lyses cells in all metabolic states. Lysostaphin also hydrolyzes glycine-rich proteins such as insoluble elastin. .Both activities have a pH optimum in the neutral range and are inhibited by agent that would chelate the endogenous zinc, suggesting that zinc interferes directly with the catalytic activity of the enzyme. Lysostaphin has been in animals and topically in man against certain infections. It is used as a research and diagnostic tool. Because it lyses staphylococcus efficiently, it is widely used when preparing staphylococcal DNA or other cellular components for genetic and biochemical studies and for the preparation of protoplasts for transformation. Preparation and analysis of bacterial DNA has become a powerful tool used by clinical and other microbiologists in studies aimed at tracing source of infection or bacterial contamination.
Lysostaphin is an endopeptidase specific for the cell wall peptidoglycan of Staphylococcus species. It has a molecular weight of 27 kDa, comprises 246 amino acids, and an isoelectric point of 10.5–11.0. The enzyme cleaves the Gly-Gly bond in the pentaglycine subunit of the peptidoglycan, lysing cells in all metabolic states, and also hydrolyzes glycine-rich proteins such as insoluble elastin. Both activities have a neutral pH optimum and are inhibited by agents that chelate endogenous zinc, indicating zinc involvement in catalysis. Lysostaphin has been used in animals and topically in humans against certain infections, and serves as a research and diagnostic tool for preparing staphylococcal DNA, cellular components, and protoplasts for transformation.
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Hangzhou Lion Biotechnology Co., Ltd. is a premier leather products export company, established in 2010 and based in China. With a decade of experience, Hangzhou Lion Biotechnology Co., Ltd. has built a reputation for delivering high-quality leather goods to clients across the globe. The company specializes in a wide range of leather products, including bags, wallets, belts, and custom leather accessories, all crafted with precision and attention to detail. Leveraging advanced manufacturing techniques and stringent quality control processes, Hangzhou Lion Biotechnology Co., Ltd. ensures that each product meets the highest standards. The company’s commitment to excellence, timely delivery, and customer satisfaction has made it a trusted name in the international market.Hangzhou Lion Biotechnology Co., Ltd. continues to expand its global footprint, exporting its superior leather products to various countries, while maintaining strong relationships with clients worldwide.
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Hangzhou Lion Biotechnology Co., Ltd., a reliable B2B trader from China, dispatches Lysostaphin primarily through the port at China. Packaging types (e.g., bulk, custom, eco-friendly) and estimated pricing may vary based on order volume and destination. To get detailed logistics and pricing information, reach out via the Inquire Now button or Sign Up for direct supplier interaction.